A history of trachoma

This incredibly painful eye condition has been blinding humans for thousands of years. Our timeline tracks the disease’s history, from the Ice Age to the present day.

What is trachoma, and how does it spread?

More about the disease

Trachoma is one of the world’s oldest recorded diseases: evidence suggests it has been around for more than 10,000 years.

Its footprint can be found throughout history, from Ice Age skeletons and ancient manuscripts to Hollywood films. But it wasn’t until the 20th century that the cause of the disease was discovered, enabling it to be treated.

You can learn more about the disease in our timeline below. For more details, view our extended timeline in PDF format, which contains added information.

8000BC

Trachoma is thought to have been present in Australia as far back as the Ice Age. Skeletons found by archaeologists show some of the earliest evidence of trachoma: lesions on the skulls suggest they often had chronic eye infections.

2000BC

Hieroglyphs on ancient Nubian tombs in Sudan show eyes and tweezers, which are still used today by trachoma patients to pluck out their eyelashes and ease the pain. Trachoma was also mentioned in the Ebers Papyrus, a collection of Egyptian medical notes from 1500BC.

800s

Many textbooks were written in Arabic about eyes, in which Arab authors used the term ‘jarab’, meaning scabies, to describe trachoma.

1200s

Italian friar Francis of Assisi visited the Middle East and returned with severe trachoma. He was blind when he died in 1226, although legend suggests he lost his sight because of the tears he’d shed for the sins of the world.

1805

A black-and-white photo showing the original Moorfields Eye Hospital building.

Moorfields Eye Hospital – one of the most famous eye hospitals in the world – opened in London to treat trachoma. The disease had become a serious health issue in the UK and Europe, spread by soldiers returning from the Middle East. Many tried to escape military service by using ointment to fake trachoma.

1814

English poet William Wordsworth is said to have had recurring bouts of trachoma during the latter part of his life. He wrote about his fear of losing his sight in the long poem ‘The Excursion’.

1842

An illustration from Nicholas Nickleby showing character Wackford Squeers fighting with a man as a crowd looks on.

Charles Dickens’ novel Nicholas Nickleby is thought to have been inspired by a Yorkshire boarding school devastated by trachoma. The character of headmaster Wackford Squeers mirrors real-life head William Shaw, who was put on trial after several students went blind because of ‘neglect’ (although it’s likely they had trachoma).

1900s

Immigrants arriving in the US on Ellis Island had their eyelids checked for trachoma using a buttonhook (a tool used to fasten tight buttons) – they often warned each other to ‘beware the buttonhook men’. Anyone found to have the disease was either sent home or treated on the island before being allowed into the country.

1930s

Chinese medical researcher Dr Tang Feifan identified the bacteria that cause trachoma, enabling it to be treated with antibiotics. He continued his research during the 1950s: after experimenting on chicken eggs, it’s claimed he then infected himself, braving the pain for 40 days to collect valuable data. The disease was eventually eliminated in most higher-income countries by the mid-20th century.

1974

In Francis Ford Coppola’s film The Godfather Part II, the character of Vito Corleone is shown passing through Ellis Island as a young boy during his immigration to the US. During one scene, he is seen having his eyes checked for trachoma.

1993

Pink Zithromax tablets are placed into a patient's outstretched hand.

Scientists published an article discussing an antibiotic called azithromycin, known as Zithromax®, which they said could treat trachoma. As part of their research, they carried out the first trials of the medication in The Gambia. Zithromax® is now the most common way to treat the disease.

2012

Oman became the first country to eliminate trachoma as a public health problem, as certified by the World Health Organization. Several other countries reached this milestone between 2016 and 2018 (Morocco, Mexico, Cambodia, Laos, Ghana, Nepal and Iran), with The Gambia following in 2021, Malawi in 2022, and Benin and Mali in 2023.

Looking to the future

Sightsavers is continuing to work with pharmaceutical companies, donors, governments and non-government organisations to commit to banishing trachoma for good. Read about our progress

For more details about trachoma, view our extended timeline in PDF format, which contains added information.

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